Rasagiline Impurity 75 HCl CAS 1016719-48-4 (free base)
| CAS No. | 1016719-48-4 (free base) |
| Molecular Formula | C12H17N |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Rasagiline Impurity 75 HCl (CAS 1016719-48-4 (free base)) is a certified pharmaceutical impurity reference standard with the molecular formula C12H17NHCl and a molecular weight of 211.73 g/mol.
The molecular framework of Rasagiline Impurity 75 HCl (C12H17NHCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Rasagiline Impurity 75 HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H17N HCl |
| Molecular Weight | 211.73 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Rasagiline Standards
- Rasagiline Impurity 16 (CAS 100516-95-8)
- Rasagiline Impurity 42 (CAS 1028-21-3)
- Rasagiline Impurity 16 HCl (CAS 10409-00-4)
- Rasagiline Impurity 43 (CAS 108701-34-4)
- Rasagiline Impurity 52 (CAS 113535-01-6)
- Rasagiline Impurity 20 (CAS 1166392-42-2)
- Rasagiline Impurity 73 (CAS 1175018-73-1(free base))
- Rasagiline Impurity 13 HCl (CAS 1175018-75-3)
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- Neuropeptide Y (3-36) (human, rat) trifluoroacetate salt (CAS 150138-78-6)
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